Table 2.

Scaffold Options for Oral Mucosa Regeneration

Materials	Pros	Cons	Representatives
Synthetic materials	Reproducible; turnable structural and mechanical properties; unlimited availability	Cyto- and biocompatibility	Poly-(l)-lactic acid, polyglycolic acid
Acellular dermis	Preservation of basement membrane	Suboptimal cell ingrowth	Deepidermized dermis, AlloDerm
ECM protein-based scaffolds	Biocompatibility	Suboptimal mechanical and physical properties	Collagen, fibrin, hyaluronic acid
Hybrid scaffolds	Improved biodegradable and biocompatible properties	Complicated production process	Combined natural and synthetic matrices

ECM, extracellular matrix.