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. 2010 Nov 26;39(4):e25. doi: 10.1093/nar/gkq1187

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Performance of the different programs in the manually evaluated regions for the three transcription factors NRSF (A and D), SRF (B and E) and Max (C and F). The plots show how the FDR increases with percentage recovery of true peaks. Note the difference in scale on the FDR-axes for plots (A–C) compared to (D–F). Plots (A–C) show results when no background data is used in the analysis, whereas D–F show results when additional background data is included. The latter plots also show results from the meta-approach described in this study.