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. 2010 Oct 15;39(4):1419–1426. doi: 10.1093/nar/gkq932

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Equilibrium distribution of DNA molecules over the linking number difference, . To analyze the distribution, radioactively labeled DNA topoisomers were separated by agarose gel electrophoresis (A) and the gel was scanned by Phosphorimager (B). The symbols OC and L mark the bands of open circular and linear DNA molecules, correspondingly. (C) Linearized representation of the distribution. The slope of the line on the plot is specified by the distribution variance (see text for details).

Inline graphic — Equilibrium distribution of DNA molecules over the linking number difference, . To analyze the distribution, radioactively labeled DNA topoisomers were separated by agarose gel electrophoresis (A) and the gel was scanned by Phosphorimager (B). The symbols OC and L mark the bands of open circular and linear DNA molecules, correspondingly. (C) Linearized representation of the distribution. The slope of the line on the plot is specified by the distribution variance (see text for details).