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Mutations at the blunt-ended dsRNA-binding surface affect RNA binding by RIG-I CTD. (A) Binding studies of wild-type and mutants of RIG-I CTD with the 14-bp blunt-ended dsRNA by EMSA. (B) Binding studies of RIG-I CTD mutants with a 14-bp 5′ ppp dsRNA. (C) Binding studies of RIG-I CTD mutants with a 13-nt 5′ ppp ssRNA.
