Skip to main content
. Author manuscript; available in PMC: 2012 May 9.
Published in final edited form as: Chemistry. 2010 Nov 9;17(2):10.1002/chem.201002195. doi: 10.1002/chem.201002195

Figure 1.

Figure 1

Inhibition of invasion of MDA-MB-231 cells by 13e. Mean cell numbers (with standard error of the mean) invading through Matrigel in a transwell assay are shown (n=6–8 replicates from three independent experiments). Asterisks denote statistically significant differences from the control by unpaired, two-tailed Student’s t-tests (with P<0.0006 at all three concentrations). The minimum lethal concentration (MLC) for 13e under the conditions of the cell invasion assay was 50 μM. In the cell invasion assay, cells were at a lower density than in the wound closure assay, and compounds were added at the same time as the cells, rather than after attachment and growth.