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. Author manuscript; available in PMC: 2012 Mar 4.
Published in final edited form as: Org Lett. 2011 Jan 26;13(5):1118–1121. doi: 10.1021/ol103149b

Table 2.

Synthesis of Tetra-substituted Pyrroles B

graphic file with name nihms268343u3.jpg
Pyrrole Ar R1 R2 yield %
B1 Ph Me Pr 43
B2 Ph 4-MeO-Ph graphic file with name nihms268343t4.jpg 80
B3 Ph 4-MeO-Ph 2,6-Cl-Ph 70
B4 Ph 4-MeO-Ph 3,5-Br-Ph 70
B5 Ph 4-O2N-Ph 3,4,5-MeO-Ph 19
B5 Ph 2,4,6-i-Pr-Ph 3,4,5-MeO-Ph 24
B5 Ph 4-Me-Ph 3,4,5-MeO-Ph 45
B5 Ph 4-MeO-Ph 3,4,5-MeO-Ph 59
B5 Ph Me 3,4,5-MeO-Ph 78