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. Author manuscript; available in PMC: 2012 Mar 4.
Published in final edited form as: Org Lett. 2011 Jan 26;13(5):1118–1121. doi: 10.1021/ol103149b

Table 3.

Synthesis of Tetra-substituted Pyrroles B

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pyrrole Ar R2 E yield %
B5 Ph 3,4,5-MeO-Ph CN 80
B6 Ph 2-Cl-6-F-Ph CN 76
B7 Ph 4-MeO-Ph CN 55
B8 4-MeO-Ph 3,4,5-MeO-Ph CN 85
B9 Ph 4-Br-Ph CN 73
B10 4-MeO-Ph 4-MeO-Ph 4-MeO-Bz 48
B11 Ph 4-O2N-Ph SO2Ph 28
B12 Ph 4-Br-Ph SO2Ph 40
B13 Ph 3,4,5-MeO-Ph SO2Ph 52
B14 Ph 3,4,5-MeO-Ph COOEt 57
B15 Ph 2,6-Cl-Ph CONH2 48
B16 Ph 4-MeO-Ph CONH2 93
B17 4-MeO-Ph 4-MeO-Ph CONH2 89