Fig. 2.

Influence of Bach1 ablation on hepatic lipid metabolism. (A) Liver sections from wild type (A and B) and Bach1^−/− mice (C and D) fed either regular chow (left panels) or MCD diet (right panels) were processed for haematoxylin & eosin (HE) staining. (original magnification 200×). (B) Hepatic triglyceride concentrations in wild type (open bars) and Bach1^−/− (closed bars) mice (n = 5/each group) were determined after feeding either regular chow or MCD diet. (C) Hepatic mRNA expressions of PPARα and MTP were quantified (n = 5/each group) by quantitative real-time PCR. *p<0.05, regular chow vs MCD diet. ^†p<0.05, wild type vs Bach1^−/− mice.