Table 2.

Genetic networks up-regulated by pioglitazone treatment analyzed by Pathway Analysis

Network ID	Genes in Network	Score	Focus Genes	Top Function
1	APOB, BACE, CANX*, CDK4, ERP70, GAPD, HSP60, HSPA4, HSPA5, HSPCA, IGK@, MYC, PPP1CC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB10, PSMB2, PSMB3, PSMB4, PSMB5, PSMB6, PSMB7, PSMB8, PSMB9, SERPINA1, TRA@, TYR, TYRP1, VWF	14	6	Cell cycle, Cell-to-Cell Signaling and Interaction, Cancer

Bold - Up[-]regulated fo[c]us genes. Gene/Protein identified that made the user-defined cutoff and map to the Global Molecular Network are displayed with bold text. *-Duplicates. Gene IDs marked with asterisks indicate that multiple identifiers from our input list mapped to a single gene in the Global Molecular Network.

CANX, calnexin; ERP70, endoplasmic reticulum stress protein 72; HSP60, heat-shock protein 60; HSPA5, heat-shock 70 kD protein 5; HSPCA, heat-shock protein 86; PSMB4, proteasome subunit beta type4.