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. Author manuscript; available in PMC: 2011 Feb 28.
Published in final edited form as: Oncogene. 2007 Jul 23;27(6):794–802. doi: 10.1038/sj.onc.1210674

Figure 5.

Figure 5

Exogenous estrogen stimulated abnormal growth in postpubertal Brca1f/f;MMTV-Cre mice. Mammary gland whole mounts of 6-month-old placebo (a, c, e and g) and 17β-estradiol-treated (b, d, f and h) intact (a–d) and ovariectomized (ovex) (e–h) Brca1f/f;MMTV-Cre and wild-type female mice. Thick arrowheads indicate areas of abnormal ductal growth found in the 17βestradiol-treated Brca1f/f;MMTV-Cre mice. Thin arrows indicate normal-appearing ductal structures in the placebo-treated Brca1f/f;MMTV-Cre and placebo and 17β-estradiol-treated wild-type mice. Magnification, × 4; scale bar, 200 µm.