Table 2.
Influence of FTO genotype on clinical parameters. All values adjusted for age and gender. (Measures including triglycerides also adjusted for intrinsic intraindividual variation; aip – atherogenic index of plasma)
TT | TA | AA | dominant | co-dominant | ||||
---|---|---|---|---|---|---|---|---|
Genotype count (%) | 1625 (33.2) | 2391(48.8) | 881(18) | |||||
Mean | SE | Mean | SE | Mean | SE | |||
BMI (kgm−2) | 30.16 | 0.14 | 30.80 | 0.12 | 31.29 | 0.19 | 8.8×10−6 | 8.5×10−7 |
Pulse pressure (mmHg) | 62.77 | 0.25 | 63.31 | 0.17 | 63.84 | 0.31 | 0.021 | 0.026 |
Mean arterial Pressure (mmHg) | 98.5 | 0.2 | 98.8 | 0.1 | 99.2 | 0.2 | 0.017 | 0.049 |
Glycated Hemoglobin (%) | 7.7 | 0.03 | 7.7 | 0.02 | 7.8 | 0.04 | 0.127 | 0.185 |
HDL(mmolL−1) | 1.32 | 0.008 | 1.30 | 0.005 | 1.29 | 0.01 | 0.008 | 0.035 |
Triglycerides (mmolL−1) | 2.36 | 0.03 | 2.44 | 0.02 | 2.52 | 0.03 | 0.002 | 0.002 |
Total Cholesterol (mmolL−1) | 4.83 | 0.02 | 4.84 | 0.01 | 4.85 | 0.03 | 0.718 | 0.554 |
aip | 0.20 | 0.006 | 0.22 | 0.004 | 0.24 | 0.08 | 0.003 | 0.002 |