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Activity of conjugate 3 against Mtb extensively drug resistant (XDR) strains19 and M. smegmatis (MIC in μg/mL).
| Strain 8 HRESPOCTh |
Strain 9 HREPKOTh |
Strain 10 HRESPO |
Strain 11 HRESPOCTh |
M. smegmatis |
|---|---|---|---|---|
| 0.31 | 0.078 | 0.625 | 0.31 | >5 |
Abbreviations for Tables 2&3: Resistance to: H=isoniazid, R=rifampicin, E=ethambutol, Z=pyrazinamide, S=streptomycin, C=cycloserine, T=ethionamide, K=kanamycin, P=p-aminosalicylic acid, Rb=rifabutin, Th=thioacetazone, O=ofloxacin.
