Figure 1. Hematopoiesis.
Hematopoietic stem cells (HSCs) with extensive self-renewal capacity give rise to multipotent progenitor cells (MPPs), which can in turn differentiate into committed lymphoid progenitors (CLPs) or committed myeloid progenitors (CMPs). These cells further differentiate into committed progenitors and eventually mature blood cells. *Indicates cells capable of forming multilineage colonies in methylcellulose media (methylcellulose does not support the growth of lymphoid cells).