Fig. 6. NTPDase1 deficiency increases IL-1β production in inflammatory air pouches.
Air pouches were raised on the back of female Entpd1+/+ and Entpd1−/− C57BL/6 mice. At the indicated time in hours (H) post s.c. injection of LPS in the pouches, inflammatory exudates were collected and analyzed for IL-1β level by ELISA. Data show mean ± SEM of n = 7–8 mice per group. *p<0.05, one-way ANOVA with Bonferroni multiple comparison test.