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. Author manuscript; available in PMC: 2011 Feb 28.
Published in final edited form as: Ann Neurol. 2009 Jan;65(1):67–75. doi: 10.1002/ana.21536

Fig 5.

Fig 5

Complement cytotoxicity is attenuated after the treatment with rEV576. Rat serum diluted 1/2, 1/4, 1/8, or 1/16 was incubated for 1 hour with rhabdomyosarcoma cells (5 × 104 cells/well). Treatment with complement inhibitor resulted in a significant reduction of serum toxicity of severe (S-EAMG) (A) and mild experimentally acquired myasthenia gravis (M-EAMG) (B) rats (p < 0.01). Results are expressed as relative luminescent unit (RLU) ± standard error of the mean of six rats per experimental group. (A) Black circles represent S-EAMG group; dark gray squares represent S-EAMG + rEV576 group; light gray triangles represent normal rat serum. (B) Black circles represent M-EAMG group; dark gray squares represent M-EAMG + rEV576 group; light gray triangles represent normal rat serum.