Fig. 6.

Morphological degeneration significantly affects dendritic signal propagation. a Anatomical reconstruction (left) and outward morphoelectrotonic transform (right) of a typical young rhesus layer 3 pyramidal cell projecting from superior temporal cortex to the PFC. Transformed apical dendrites are shown in red. b Similar to a, for an analogous neuron from an old rhesus monkey. c Effects of age-related degeneration on mean outward and outward attenuation transforms. Histograms shows mean ± SEM for the young (n = 24) and old (n = 19) neuron groups (*P<0.05, **P<0.01) [modified from Kabaso et al. (2009)]