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. Author manuscript; available in PMC: 2011 Feb 28.
Published in final edited form as: Bioorg Med Chem Lett. 2009 Mar 25;19(14):3928–3931. doi: 10.1016/j.bmcl.2009.03.085

Table 2.

Inhibitory activity on recombinant HDAC1 and HDAC3.

Compds HDAC1
IC50, µMa 		HDAC3
IC50, µMa
1 191(±27.8) 46.9 (±17.1)
10 4.7 (±0.2) 1.3 (±0.7)
13 532 (±37.7) 69.3 (±6.5)
15 83.9 (±21.4) 4.3 (±1.2)
16 9.2 (±0.5) 2.2 (±0.02)
11 20.5 (±3.0) 5.6 (±0.5)
12 7.3 (±1.4) 3.4 (±0.3)
14 84.2 (±15.9) 27.2 (±8.5)
a

Values are means of two experiments with standard error given in parentheses.