FIGURE 7:

Schematic representation of the factors that regulate Cdc42p polarization in the daughter cell plasma membrane. Cdc42p is trafficked to the tip of the daughter cell through both the Bgl2p and invertase pathways. Once at the bud tip, Cdc42p may diffuse laterally along the plasma membrane. Endocytosis internalizes Cdc42p from the plasma membrane. The internalized Cdc42p can be carried as cargo back to the daughter cell through the endosomal compartments along the invertase pathway. Cdc42p can also be recycled from the daughter cell membrane by Rdi1p. The septin ring acts as a diffusion barrier to prevent Cdc42p from diffusing out of the daughter cell. PM, plasma membrane; TGN, trans-Golgi network. Cdc42p is indicated as small red circles with lipid tails.