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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: J Inorg Biochem. 2011 Jan;105(1):58–62. doi: 10.1016/j.jinorgbio.2010.09.008

Figure 6.

Figure 6

Effect of Cr(d-Phe)3 on insulin signaling in insulin resistant myotubes. Myotubes treated with palmitate (0-1 mM) for 16 h prior to stimulation with insulin (10 nM, 10 min), and immunoblotted with the indicated antibodies in the absence (A) or presence (B) of chromium (100 μM) prior to stimulation with insulin (10 nM, 10 min) and immunoblotted for p-Akt, and p-JNK. Blots were reprobed for total-Akt and total JNK respectively (C). Concentration dependent effect of chromium on the insulin stimulated- phosphorylation of Akt and insulin receptor β in the presence and absence of palmitate.