Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Mar;4(2):268–276. doi: 10.1242/dmm.002998

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2011. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms

PMC Copyright notice

Fig. 4. — The SeAP transgene is expressed in the endocrine lineage the embryonic pancreas of BAC NEUROG3-SeAP/EGFP transgenic mice. (A,B) Enzymatic SeAP activity (purple) was colocalized with immunohistochemical staining of endogenous neurogenin-3 (brown, A) in E14.5 fetal pancreases or ductal marker DBA lectin (brown, B) in E18.5 fetal pancreases. Scale bar: 50 μm. (C) Pancreases were harvested from E12.5 embryos and placed in culture at day 1. At 24-hour intervals, SeAP activity in the media was assayed [reported as relative light units (RLUs)], and media was replaced. The solid line indicates media cultured with transgenic pancreases; the dashed line indicates media cultured with non-transgenic pancreases. Data represent mean ± s.e.m. from six pancreases in each group.