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. 2011 Feb 28;6(2):e14736. doi: 10.1371/journal.pone.0014736

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Zhu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. Effects of propranolol on the infarct size in rats with myocardial infarction. Left panel: the white portion of the coronal sections of the left ventricular wall represents the infarct area. Right panel: the size of infarct area was expressed as the percentage of a standard coronal section. **p<0.01 vs. MI (two-way paired t-test), n = 5. B. Count of miRNAs with expression levels varied by at least ±0.5 from the levels in Control. The right upper heatmap shows the miRNA expression similarity between groups. MI, myocardial infarction; MI-PRO, myocardial infarction-propranolol; NMI-PRO, non-myocardial infarction-propranolol. C. Quantification of miR-1 expression. Relative level of miR-1 normalized to control; ***p<0.0001 vs. control; ##p<0.01 vs. MI (two-way paired t-test), n = 8.