Skip to main content
. 2011 Feb 28;6(2):e17299. doi: 10.1371/journal.pone.0017299

Figure 5. Quantitative real-time PCR analysis of selected sphingolipid-related genes in the anterior cingulate cortex (ACC), amygdala (AMY) and visual cortex (VC) of control (Con) and Parkinson's disease (PD) tissues.

Figure 5

The expression of genes involved in the sphingolipid biosynthetic pathway (see Fig. 4B) was assessed by qRT-PCR. Data for all genes are expressed relative to the control values (Con  =  white bars, assigned a value of 1.0; PD  =  black bars). The data are presented separately for ACC (A), AMY (B) and VC (C). Serine palmitoyltransferase, long chain base subunit 2 (SPTLC2); follicular lymphoma variant translocation 1 (FVT1); degenerative spermatocyte homolog 1, lipid desaturase (DEGS); sphingomyelin synthase 1 (SGMS1); UDP galactosyltransferase 8A (UGT8A); and galactose-3-O-sulfotransferase 1 (GAL3ST1). Data represent mean ± SEM, *p<0.05 by t-test.