Table 2.
End organ damage caused by lead poisoning
Gastrointestinal | ‘Lead colic’ |
Anorexia, constipation, nausea and vomiting | |
Hepatitis | |
Neurological | Peripheral neuropathy |
Cerebral oedema | |
Behavioural change and acute psychosis | |
With higher levels: encephalopathy, seizures, coma and eventually death | |
Haematological | Anaemia |
Haemolysis | |
Renal | Fanconi-like syndrome |
Chronic interstitial nephropathy | |
Cardiovascular | Myocarditis |
Hypertension (chronic exposure) | |
Developmental (paediatric) | Neurodevelopmental delay and learning difficulties |
Growth retardation | |
Hearing impairment | |
Reproductive system | Men: low sperm count and abnormal sperm morphology |
Women: miscarriage, prematurity, low birth weight and contamination of breast milk | |
Other | Gout |
Gum discolouration |