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Schematic representation of the potential of combined use of WPSS, a disease-related prognostic scoring system, and MDS-CI in clinical decision making in MDS. It should be noted that we have recently shown that in MDS patients hemoglobin levels lower than 9 g/dL in males and 8 g/dL in females are independently related to reduced overall survival.34 Thus, severe anemia in MDS can be defined as a hemoglobin level below these thresholds.
