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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Neuromuscul Disord. 2010 Dec 30;21(3):204–213. doi: 10.1016/j.nmd.2010.12.003

Figure 4. Effect of Ruc-C124A reporter on the detection of patient autoantibodies.

Figure 4

The larger cohort of MG patients (N=63) and controls (N=29) was revaluated using (A) AChR-α1-Δ5 and (B) AChR-α1-Δ1 fused to the Ruc-C124A mutant reporter. Each point represents the average amount of fusion protein immunoprecipitated in two independent experiments by each patient in LU. The long solid line shows a cutoff based on the average plus three standard deviations of the controls. The shorter solid lines indicate the average of each group.