Table 1.
IC50 values of the fluorinated α-MSH analogues and their expected and measured molecular weight (M.W.) for [M+H]+ by ESI-MS or MALDI-TOF-MS
| Peptides | Expected M.W. | Measured M.W. | IC50 (nM) |
|---|---|---|---|
| 19F-FP-RMSH-1 | 1878.2 | 1878.1 | 6.1 ± 0.6 |
| 19F-FP-RMSH-2 | 1878.2 | 1878.1 | 33.7 ± 3.0 |