Table 1. Summary of mutational analysis.

Constructa	N-terminal	RRM1	RRM2	NOPS/coiled-coil	Dimerizationb	Viabilityc	Radioresistanced	Relocalizatione
PSF wt	•	•	•	•	yes	100%	yes	yes
PSF Δ1		•	•	•	yes	58%	no	slight
PSF Δ2			•	•	yes	22%	no	no
PSF Δ3				•	no	11%	no	no
PSF Δ4	•	•		•	yes	81%	partial	yes

^aRefer to Fig. 1C for schematic

^bEstimated based on Supplementary Figure 2.

^cMean of two independent experiments, Fig. 1 and data not shown

^dBased on Fig. 1, Panel E

^eBased on Fig. 3