Table 1.
Reproductive and metabolic characteristics of the PCOS and control groups.
| PCOS (n=31) |
Controls (n=11) |
P-value | |
|---|---|---|---|
| Demographics | |||
| Age (years) | 30.5 ± 5.5 | 32.1 ± 7.5 | 0.45 |
| Body mass index (kg/m2) | 36.8 ± 10.6 | 28.6 ± 5.5 | 0.02 |
| Waist-hip ratio | 0.87 ± 0.06 | 0.82 ± 0.05 | 0.39* |
| Reproductive characteristics | |||
| Testosterone (ng/dl) | 77.8 ± 37.3 | 30.9 ± 9.3 | <0.01* |
| Free and Weakly bound Testosterone (ng/dl) | 21.2 ± 9.7 | 7.5 ± 3.4 | <0.01* |
| Ferriman-Gallwey score | 14.6 ± 6.5 | 3.4 ± 4.7 | <0.01* |
| Mean ovarian volume (cm3) | 17.9 ± 11.6 | 7.1 ± 4.2 | 0.02* |
| Prevalence of polycystic ovary morphology† | 26 (93%) | 1 (9%) | <0.01* |
| Metabolic characteristics | |||
| Systolic blood pressure (mmHg) | 116.7 ± 14.0 | 114.8 ± 9.5 | 0.75* |
| Diastolic blood pressure (mmHg) | 67.1 ± 11.0 | 65.7 ± 7.3 | 0.32* |
| Total cholesterol (mg/dl) | 195.5 ± 35.2 | 172.5 ± 37.3 | 0.05** |
| LDL Cholesterol (mg/dl) | 122.7 ± 28.4 | 104.0 ± 32.1 | 0.09** |
| HDL Cholesterol (mg/dl) | 45.7 ± 10.9 | 48.5 ± 9.1 | 0.92* |
| Triglycerides (mg/dl) | 136.0 ± 67.2 | 99.6 ± 50.1 | 0.24* |
| Fasting glucose (mg/dl) | 86.8 ± 8.6 | 86.0 ± 6.5 | 0.44* |
| Fasting insulin (uU/ml) | 19.6 ± 15.2 | 14.0 ± 5.3 | 0.69* |
| Fasting glucose-Insulin ratio | 6.6 ± 3.9 | 7.0 ± 2.7 | 0.67* |
Data are presented as mean ± SD, unadjusted;
*
ANCOVA, adjusted for age, BMI, and LDL cholesterol;
**
ANCOVA, only adjusted for age and BMI.
†
Polycystic ovary morphology is defined as the presence of ≥ 12 follicles measuring 2–9 mm in either ovary. N (%) and Fisher’s Exact test are reported.