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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Free Radic Biol Med. 2011 Jan 12;50(7):848–853. doi: 10.1016/j.freeradbiomed.2011.01.004

Fig. 3. Plasma ascorbic acid concentrations in nonsmoking and smoking men and women following supplementation with vitamin C or placebos.

Fig. 3

During this double-blind, placebo-controlled, randomized crossover study, participants received 17-day treatments with ascorbic acid (500 mg twice per day) or with placebo. On Day 14, participants’ blood was collected at various intervals for 72 h and plasma ascorbic acid concentrations were measured in each of the samples taken; averages of these concentrations are reported herein. Vitamin C supplementation increased ascorbic acid plasma concentrations (mean ± SD, p <0.0001, n=22), but the concentrations were not different between smokers and nonsmokers, or between men and women. These data have been published previously [26].