Table 2.
Individual and mean indifference points (s) and percent change from acute saline conditions at the acute nicotine dose that resulted in a statistically significant difference from saline (0.3 mg/kg for Lewis rats and 1.0 mg/kg for Fischer 344 rats).
| Subject Number | Saline | 0.3 mg/kg | % Change |
|---|---|---|---|
| L1 | 4.1 | 4.8 | 17.1 |
| L2 | 5.2 | 4.6 | −11.5 |
| L3 | 5.8 | 6.2 | 6.9 |
| L4 | 3.4 | 4.6 | 35.3 |
| L5 | 3.3 | 4.0 | 21.2 |
| L6 | 4.1 | 5.2 | 26.8 |
| L7 | 4.0 | 5.5 | 37.5 |
| L8 | 3.1 | 5.0 | 61.3 |
| Mean | 4.1 | 5.0 | 25.4 |
| Subject Number | Saline | 1.0 mg/kg | % Change |
| F1 | 6.6 | 13 | 97.0 |
| F2 | 5.2 | 11.2 | 115.4 |
| F3 | 4.4 | 7.3 | 65.9 |
| F4 | -- | -- | -- |
| F5 | 6.1 | 5.0 | −18.0 |
| F6 | 3.9 | 4.7 | 20.5 |
| F7 | 4.6 | 13.1 | 184.8 |
| F8 | 4.2 | 3.7 | −11.9 |
| Mean | 5.0 | 8.3 | 59.4 |