Table 2.
KEGG ID | Pathway name Class |
No. of SNPs P < 0.05 |
No. of SNPs in pathway | Number of significantly associated SNPs with P | ||||
---|---|---|---|---|---|---|---|---|
E-05 | E-04 | E-03 | E-02 | P | ||||
00040 | Pentose and glucuronate interconversions Metabolism; Carbohydrate Metabolism |
11 | 63 | 0 | 1 | 2 | 8 | 0.022 |
04540 | Gap junction Cellular Processes; Cell Communication |
95 | 1,366 | 1 | 0 | 16 | 78 | 0.037 |
00500 | Starch and sucrose metabolism Metabolism; Carbohydrate Metabolism |
22 | 237 | 0 | 2 | 4 | 16 | 0.042 |
00604 | Glycosphingolipid biosynthesis ganglio series Metabolism; Glycan Biosynthesis and Metabolism |
20 | 216 | 0 | 0 | 4 | 16 | 0.051 |
00230 | Purine metabolism Metabolism; Nucleotide Metabolism |
106 | 1,618 | 1 | 2 | 16 | 87 | 0.054 |
04130 | SNARE interactions in vesicular transport Genetic Information Processing; Folding, Sorting and Degradation |
19 | 206 | 0 | 4 | 1 | 14 | 0.060 |
03022 | Basal transcription factors Genetic Information Processing; Transcription |
11 | 105 | 0 | 0 | 4 | 7 | 0.062 |
04910 | Insulin signaling pathway Cellular Processes; Endocrine System |
61 | 889 | 2 | 6 | 9 | 44 | 0.071 |
04350 | TGF-beta signaling pathway Environmental Information Processing; Signal Transduction |
43 | 586 | 0 | 1 | 9 | 33 | 0.077 |
04330 | Notch signaling pathway Environmental Information Processing; Signal Transduction |
25 | 321 | 0 | 0 | 4 | 21 | 0.087 |
04614 | Renin-angiotensin system Cellular Processes; Endocrine System |
8 | 78 | 0 | 0 | 1 | 7 | 0.092 |
KEGG ID, Kyoto Encyclopedia of Genes and Genomes pathway identifier (hsa*); P, P-value of permutation test; SNP, single nucleotide polymorphism