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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Jan 7;1812(4):439–446. doi: 10.1016/j.bbadis.2011.01.002

Fig. 4.

Fig. 4

Signaling associated with muscle hypertrophy is activated in α7BX2-mdx/utr−/− mice. mTOR and p70S6K phosphorylation were measured in muscle from 5 week-old wild type, mdx, mdx/utr−/−, and α7BX2-mdx/utr−/− mice (4–6/grp). (A) mTOR phosphorylation was significantly increased only in α7BX2-mdx/utr−/− muscle compared to wild type mice. (B) p70S6K phosphorylation was significantly increased in all groups compared to wild type muscle, and was higher in α7BX2-mdx/utr−/− mice compared to mdx/utr−/− mice that did not express the transgene. *=vs. wild type, #=vs. mdx, and ˆ=vs. mdx/utr−/− (P<0.05).