Table 1.
Criteria | Components/Formula | Cut-offs |
---|---|---|
ARA [19] and modified | No fatigue (used only for ARA, not for modified ARA criteria) | 5/6 for ARA criteria and 4/5 for modified |
ARA [20,21] | No joint pain by history | ARA; 2 months required |
No joint tenderness or pain on motion | ||
No soft tissue swelling in joints or tendon sheaths | ||
Morning stiffness for not more than 15 minutes | ||
ESR of less than 30 mm/hour in women and less than 20 mm/hour in men | ||
DAS [20] | [0.54 × √(Ritchie)] + [0.065 × SJC44] + [0.33 × ln (ESR)] + [0.0072 × GH (mm)] | Less than 1.6 |
DAS28 [21] | [0.56 × √(TJC28)] + [0.28 × √(SJC28)] + [0.70 × ln (ESR)] + [0.014 × GH (mm)] | Less than 2.6 (less than 2.4 also proposed) [28] |
SDAI [28] | SJC28 + TJC28 + PGA (cm) + EGA (cm) + CRP (mg/dL) | Not more than 3.3 |
CDAI [54] | SJC 28 + TJC28 + PGA (cm) + EGA (cm) | Not more than 2.8 |
ARA, American Rheumatism Association; CDAI, clinical disease activity index; CRP, C-reactive protein; DAS, disease activity score; DAS28, disease activity score with 28-joint assessment; EGA, evaluator global assessment of disease activity; ESR, erythrocyte sedimentation rate; GH, global health by visual analogue scale; ln, natural logarithm; PGA, patient global assessment of disease activity; Ritchie, Ritchie articular index; SDAI, simplified disease activity index; SJC28, 28 swollen joint count; SJC44, 44 swollen joint count; TJC28, 28 tender joint count.