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. 2010 Dec 29;12(6):R224. doi: 10.1186/ar3211

Figure 5.

Figure 5

Increased IL-1β, PTX-3 and PROKR2 mRNA and protein levels in mice lacking Mmp8. (a) IL-1β, pentraxin-3 (PTX-3) and prokineticin receptor 2 (PROKR2) mRNA levels were measured by quantitative real-time PCR in arthritic joints of Mmp8-/- mice (n = 6) and Mmp8+/+ mice (n = 6) at day 7 after intraperitoneal serum injection. Levels of IL-1β (b) and PTX-3 (c) proteins were measured by ELISA in extracts from arthritic joints of mice at day 7 after intraperitoneal serum injection. Values expressed as mean ± standard error of the mean; *P < 0.05, by two-sided Mann-Whitney U test.