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Increased PROKR2 expression in Mmp8-deficient mice. Protein expression of prokineticin receptor 2 (PROKR2) was determined by western blot in arthritic joints of six Mmp8-/- mice and six Mmp8+/+ mice at 7 days after arthritis induction. Densitometric analysis of PROKR2 and that normalized with the intensity of actin is shown. (a) Data represent mean ± standard error of the mean; *P < 0.05, by Mann-Whitney U test. (b) Representative blot.
