Table 3.

Odds ratios (ORs) from logistic regression analyses of associations between the examination A ARGS-aggrecan levels in SF and progression of radiographic features of OA from examination A to examination B at 7.5 years

	Total sample		Stratified ± ROA at examination A
	n = 141		-ROA, n = 63		+ROA, n = 78
	OR	P	OR	P	OR	P
Loss of joint space	0.89 (0.80-0.99)	0.029	0.77 (0.63-0.94)	0.012	0.95 (0.82-1.10)	0.47
	0.89 (0.79-0.996)	0.043	0.77 (0.62-0.95)	0.016	0.96 (0.81-1.13)	0.60
Osteophyte progression	0.96 (0.87-1.07)	0.48	0.90 (0.76-1.07)	0.23	1.01 (0.88-1.15)	0.94
	0.97 (0.87-1.08)	0.59	0.92 (0.76-1.11)	0.38	0.99 (0.86-1.15)	0.93
ROA progression	0.90 (0.80-1.00)	0.059	0.87 (0.74-1.02)	0.092	0.91 (0.77-1.08)	0.30
	0.89 (0.78-1.02)	0.10	0.87 (0.72-1.04)	0.13	0.90 (0.73-1.13)	0.37

Outcomes (loss of joint space, osteophyte progression, and ROA progression) are based on progression from examination A to examination B of the scores of joint space narrowing (JSN), osteophytes, and either JSN or osteophytes or both, scored according to the OARSI atlas [27]. OR and P values are crude (italics) or adjusted for age, gender, BMI, and time between examinations A and B (plain text), with 95% confidence interval in parentheses.