Skip to main content
. 2010 Oct 20;96(1):E199–E207. doi: 10.1210/jc.2010-1647

Figure 1.

Figure 1

Determination of the parental origin of SNP alleles in CGB5 and CGB8 loci in placental genomic DNA. Panel A, Schematic presentation of the human LHB/CGB gene cluster at 19q13.33. Panel B, Amplified genomic regions specific to the CGB5 and CGB8 loci using a combination of long-range and nested PCR (connected black arrows, primers A–F in Supplemental Table 1). Panel C, Sequenced segments in the amplified CGB5 and CGB8 loci harboring marker SNPs (short red bars, primers I–L in Supplemental Table 1). Panel D, Example of a genetically informative placental tissue for the parental origin of variants: heterozygosity in placenta and homozygosity at least in one of the parents. Chr, Chromosome; kb, kilobase.