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Comparison of the kinetics for COX-1 or COX-2 linked with PGIS in COS-7 cells as determined by enzyme coupling assays.
| Enzyme reaction | Km (Converting AA to PGI2) |
½ Vmax (s) | Reference |
|---|---|---|---|
| COX-1-10aa-PGIS | 5 µM | 120 | Ruan et al. 2008a |
| COX-2-10aa-PGIS | 2 µM | 20 | Ruan et al. 2006 |
