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. Author manuscript; available in PMC: 2012 Jan 28.
Published in final edited form as: Immunity. 2011 Jan 6;34(1):108–121. doi: 10.1016/j.immuni.2010.12.012

Figure 5. Blood CXCR5+ Th subsets are altered in JDM.

Figure 5

A. Percentage of CXCR5+ cells within CD4+ T cells in samples from JDM patients (n=52), PSOA patients (n=31), and age-matched healthy controls (n=43).

B. Percentage of each Th subset within blood CXCR5+ CD4+ T cells. One way ANOVA test, ** p<0.01, *** p<0.001.

C. Ratio of CXCR5+ (Th2 + Th17) / Th1 cells. One way ANOVA test.

D. Frequency of CXCR5+ Th1 cells and ratio of (Th2+Th17) / Th1 in JDM patients with different disease activities. One way ANOVA test.

E. Frequency of CXCR5+ Th1 cells and ratio of (Th2+Th17) / Th1 in active JDM patients receiving none, intravenous corticosteroids or high-dose Ig treatments.

F. The absolute cell numbers in blood were calculated based on the complete blood cell count, lymphocyte frequency within white blood cells, and the frequency of CXCR5+ Th subsets within the lymphocyte population. Student’s t-test.