TABLE 1.
Anthropometry and biochemistry
| Lean control subjects | Obese type 2 diabetic subjects | |
|---|---|---|
| Age (years) | 47.5 ± 6.0 | 52.3 ± 2.9 |
| Weight (kg) | 76.1 ± 3.5 | 109.7 ± 3.6* |
| Height (m) | 1.80 ± 0.02 | 1.77 ± 0.02 |
| BMI (kg/m2) | 23.5 ± 1.1 | 35.0 ± 1.0* |
| Subcutaneous abdominal adipose tissue volume (L) | 1.69 ± 0.27 | 4.27 ± 0.34* |
| Visceral abdominal adipose tissue volume (L) | 0.94 ± 0.13 | 2.96 ± 0.28* |
| Systolic blood pressure (mmHg) | 133 ± 4 | 151 ± 5 † |
| Diastolic blood pressure (mmHg) | 76 ± 2 | 87 ± 2‡ |
| Fasting plasma glucose (mmol/L) | 5.3 ± 0.3 | 8.4 ± 0.5* |
| A1C (%) | 5.3 ± 0.1 | 7.2 ± 0.3* |
| Cholesterol (mmol/L) | 5.3 ± 0.3 | 4.7 ± 0.2 |
| HDL cholesterol (mmol/L) | 1.5 ± 0.1 | 1.2 ± 0.1‡ |
| Triglycerides (mmol/L) | 0.8 ± 0.1 | 2.3 ± 0.6 |
| Albumin (g/L) | 44 ± 0 | 44 ± 1 |
| Corticosteroid-binding globulin (mg/L) | 45 ± 2 | 47 ± 2 |
| Alkaline phosphatase (units/L) | 76 ± 6 | 70 ± 6 |
| γ-Glutamyltransferase (units/L) | 23 ± 5 | 45 ± 5† |
| Alanine aminotransferase (units/L) | 23 ± 4 | 39 ± 6 |
| Bilirubin (μmol/L) | 12 ± 1 | 11 ± 1 |
Data are means ± SEM for lean control subjects (n = 7) and obese men with type 2 diabetes (n = 10).
*P < 0.001;
†P < 0.05;
‡P < 0.01 vs. lean control subjects.