Table 2.
Geometric means of antibody titres as determined by ELISA.
All PkAMA1 | Protected PkAMA1 | Not protected PkAMA1 | All PkMSP119 | Protected PkMSP119 | Not protected PkMSP119 | |
---|---|---|---|---|---|---|
Post vaccination | 2,305 [855-6,214] | 2,417 [469-12,451] | 2,137 [508-8,990] | 332 [97-1,136] | 633 [109-3,671] | 118 [16-853] |
Post challenge | 79,030 [46,803-133,444] | 94,870 [40,055-224,699] | 59,000 [32,980-105,548] | 16,784 [11,104-25,369] | 17,875 [11,730-27,240] | 15,175 [4,562-50,477] |
In brackets the 95% confidence intervals. No significant differences were observed between protected or not-protected groups of animals. For both antigens and all groups, antibody levels are significantly higher after challenge.