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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Hypertension. 2010 Jun 28;56(2):232–239. doi: 10.1161/HYPERTENSIONAHA.110.149963

Figure 4.

Figure 4

The effects of A20 on fibrosis in vivo. A, Picrosirius red staining on histological sections of the left ventricle (LV) was performed on indicated groups after 8 weeks AB. The magnification of images were X400. Fibrotic areas from histological sections were quantified using an image-analyzing system (n=5). *P<0.01 vs WT/sham. #P<0.01 vs WT/AB after AB. B, Northern blot analyses of connective tissue growth factor (CTGF), collagen I, collagen III, TGF-β1, and TGF-β3 were performed to determine mRNA expression levels in indicated groups. GAPDH was used as the normalization control. Data represent typical results of 3 different experiments as mean±SEM (n=4 to 5 mice per group). *P<0.01 vs WT/sham. #P<0.01 vs WT/AB after AB.