Table 1. Published literature on clinical signs & symptoms of T.b. rhodesiense HAT.

	Buyst/1977 [18]	Boatin/1986 [29]	Wellde/1989 [35]	Mbulamberi/1987 [36]
Number of patients	385	60	96	3152
Country	Zambia	Zambia	Zambia	Uganda
Disease stage of patients	2nd stage	2nd stage	2nd stage	1st stagea
Male/female ratio	N.A.	1.73	1.53	1.1
Chancre	N.A.	5	15.6	19
Headache	66.2	73.3	95.8	95.8
Fever	31.2	71.7	36.4	96.8
Lymphadenopathy	80.5	N.A.	86.4	17.6
Itching or pruritus	N.A.	35	53.1	N.A.
Oedema of face	30.1b	21.7	3.1	27.5
Swelling of legs	N.A.	43.3	25.3	N.A.
Joint pains	N.A.	65	88.5	95
Day time sleep	N.A.	63.3	70.8	26.8c
Night time sleep	N.A.	28.3	N.A.	N.A.
Abnormal coordination	N.A.	N.A.	51	N.A.
Abnormal speech	N.A.	N.A.	38.5	N.A.
Mental confusion	17.4	N.A.	N.A.	N.A.

N.A: not applicable;

^a98.7% of the patients were in the first stage and 1.3% of the patients in the second stage of the disease;

^breported as oedema,

^creported as somnolence