Table 3. Clinical signs and symptoms at baseline and treatment outcomes.
Total (n = 138) | Tanzania (n = 69) | Uganda (n = 69) | p-value | ||||
n | % | n | % | n | % | ||
Clinical signs & symptoms | |||||||
Lymphadenopathy | 27 | 19.6 | 7 | 10.1 | 20 | 29.0 | 0.0053 |
General body pain | 132 | 95.7 | 69 | 100.0 | 63 | 91.3 | 0.0123 |
Headache | 128 | 92.8 | 65 | 94.2 | 63 | 91.3 | 0.5114 |
Fever (≥37.5°C) | 37 | 26.8 | 20 | 29.0 | 17 | 24.6 | 0.5643 |
Fever (>38.5°C) | 4 | 2.9 | 0 | 0.0 | 4 | 5.8 | 0.0424 |
Joint pains | 129 | 93.5 | 67 | 97.1 | 62 | 89.9 | 0.0847 |
Diarrhea | 9 | 6.5 | 1 | 1.4 | 8 | 11.6 | 0.0158 |
Pruritus | 21 | 15.2 | 4 | 5.8 | 17 | 24.6 | 0.0003 |
Oedema | 40 | 29.0 | 26 | 37.7 | 14 | 20.3 | 0.0244 |
Dyspnoe | 10 | 7.2 | 1 | 1.4 | 9 | 13.0 | 0.0086 |
Cough | 27 | 19.6 | 8 | 11.6 | 19 | 27.5 | 0.0183 |
Tremor | 54 | 39.1 | 43 | 62.3 | 11 | 15.9 | 0.0001 |
Hepatomegaly | 25 | 18.1 | 4 | 5.8 | 21 | 30.4 | 0.0002 |
Splenomegaly | 51 | 37.0 | 11 | 15.9 | 40 | 58.0 | 0.0001 |
Walking difficulties | 75 | 54.3 | 35 | 50.7 | 40 | 58.0 | 0.3928 |
Abnormal movements | 36 | 26.1 | 31 | 44.9 | 5 | 7.2 | <0.0001 |
Sleeping disorder daytime | 105 | 76.1 | 66 | 95.7 | 39 | 56.5 | <0.0001 |
Sleeping disorder night time | 88 | 63.8 | 64 | 92.8 | 24 | 34.8 | <0.0001 |
Strange behaviour | 25 | 18.1 | 15 | 21.7 | 10 | 14.5 | 0.2691 |
Disturbed appetite | 120 | 87.0 | 60 | 87.0 | 60 | 87.0 | 1 |
Inactivity | 100 | 72.5 | 57 | 82.6 | 43 | 62.3 | 0.0076 |
Speech impairment | 16 | 11.6 | 6 | 8.7 | 10 | 14.5 | 0.2875 |
Aggressiveness | 45 | 32.6 | 43 | 62.3 | 2 | 2.9 | <0.0001 |
Treatment outcomes | |||||||
Death | 15 | 10.1 | 7 | 10.1 | 8 | 11.6 | 0.7845 |
Cure (parasitological & clinical) | 123 | 89.1 | 62 | 89.9 | 61 | 88.4 | 0.7845 |