Table 1. Population dynamics estimates for the CRF28/29_BF epidemic.a .
Gene | μ, site−1 year−1 | Origin of the lineage | Number of effective infections | r, year−1 | λ, month |
pol | |||||
Linked locus [nt 2265–3094] | 2.60×10−3 (1.72×10−3–3.46×10−3) | 1989 (1987–1993) | 2537 (405–15320) | 1.18 (0.64–1.38) | 7.05 (6.00–12.96) |
Unlinked F locus [nt 2265–2572] | 2.69×10−3 (1.78×10−3–3.54×10−3) | 1991 (1988–1994) | 3176 (651–18028) | 1.25 (0.78–1.55) | 6.68 (5.37–10.66) |
Unlinked B locus [nt 2573–3094] | 2.55×10−3 (1.91×10−3–3.33×10−3) | 1989 (1986–1992) | 2415 (367–13994) | 1.13 (0.61–1.26) | 7.36 (6.65–13.64) |
gag | |||||
Linked locus [nt 1087–1560] | 1.94×10−3 (0.91×10−3–3.06×10−3) | 1988 (1984–1992) | 1778 (191–10212) | 1.20 (0.59–1.47) | 6.93 (5.66–14.10) |
Unlinked B locus [nt 1087–1323] | 2.02×10−3 (0.82×10−3–3.24×10−3) | 1989 (1986–1994) | 2092 (322–12273) | 1.27 (0.67–1.61) | 6.55 (5.17–12.42) |
Unlinked F locus [nt 1324–1560] | 1.95×10−3 (0.85×10−3–3.17×10−3) | 1988 (1983–1991) | 1619 (152–9867) | 1.15 (0.55–1.42) | 7.24 (5.86–15.12) |
Numbers in parentheses are the range of the 95% upper and lower high posterior density. μ, rate of nucleotide substitution; r, median rate of exponential growth; λ, epidemic doubling time.