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Catalytic activity-dependant effect LmjMCA.
A. Schematic representation of the C-terminally M2 Flag-tagged LmjMCA protein (LmjMCA-Flag) and its enzymatically inactivated form (LmjMCA-Flag H147A/C202A).
B. Generated fusion proteins were expressed in L. major parasites and analysed as in Fig. 5C. Solid arrowheads indicate intact mitochondria and open arrowheads indicate affected mitochondria.
