Change relative to baseline in hematologic and serum chemistry parameters after first, second and fourth infusion of CP-870,893 in patients at MTD or higher. ALC, absolute lymphocyte count; AMC, absolute monocyte count; Plts, platelets; Ddi, D-dimer; INR, international ratio; Hgb, hemoglobin; AST, asparate aminotransferase; ALT, alanine aminotransferase; Bili, total bilirubin. Arrows indicate treatment days (day 1, 8, 15, 22). Values expressed as mean ± SEM, n = 8–18.