Table 3.
Dose, diagnoses, time to progression and number of doses for patients with stable and progressive disease as best clinical response
Response | Patient | Dose (mg/kg) | Diagnosis | TTP (weeks) | # of doses |
SD | |||||
4001 | 0.05 | Uterine cancer | 20 | 21 | |
3004 | 0.1 | Melanoma | 19 | 16 | |
4004 | 0.1 | Melanoma | 15 | 16 | |
3005 | 0.2 | Mesothelioma | 18 | 16 | |
3009 | 0.2 | Mesothelioma | 17 | 15 | |
3006 | 0.25 | RCC | 18 | 13 | |
3008 | 0.25 | RCC | 16 | 13 | |
Median | 18 | 16 | |||
PD | |||||
3001 | 0.05 | Melanoma | 4 | ||
3002 | 0.05 | Melanoma | 7 | 8 | |
3003 | 0.05 | Breast cancer | 2 | 3 | |
4002 | 0.05 | HCC | 6 | 7 | |
4003 | 0.1 | Melanoma | 4 | 5 | |
3010 | 0.2 | Bladder cancer | 7 | 8 | |
3011 | 0.2 | Melanoma | 5 | 4 | |
3012 | 0.2 | Nasopharyngeal cancer | 4 | 5 | |
3013 | 0.2 | Breast cancer | 5 | ||
3015 | 0.2 | Neuroendocrine tumor | 7 | 8 | |
4005 | 0.2 | Melanoma | 2 | 3 | |
4006 | 0.2 | Breast cancer | 3 | 4 | |
4009 | 0.2 | Sarcoma | 3 | 4 | |
4010 | 0.2 | Melanoma | 7 | 6 | |
5001 | 0.2 | Ovarian cancer | 7 | 8 | |
5004 | 0.2 | Melanoma | 3 | 4 | |
3007 | 0.25 | Melanoma | 4 | 5 | |
4008 | 0.25 | Anal cancer | 7 | 8 | |
5002 | 0.25 | Colon cancer | 7 | 7 | |
5003 | 0.25 | Melanoma | 7 | 8 | |
Median | 4.5 | 5 |
RCC, renal cell carcinoma; HCC, hepatocellular carcinoma.