Table 3.
Correlation with clinicopathological features and molecular markers
Variables(%) | EGFR protein | EGFR mutation | pAkt | pERK | ||||||||
positive | negative | p value | positive | negative | p value | positive | negative | p value | positive | negative | p value | |
Histology | 0.15 | 0.04 | 0.17 | 0.61 | ||||||||
serous | 29(61.7) | 39(7039) | 19(79.2) | 49(62.8) | 36(73.5) | 32(60.4) | 10(58.8) | 58(68.2) | ||||
clear cell | 13(27.7) | 7(12.7) | 3(12.5) | 17(21.8) | 7(14.3) | 13(24.5) | 5(29.4) | 15(17.6) | ||||
endometrioid | 3(6.4) | 8(14.5) | 0(0.0) | 11(14.1) | 6(12.2) | 5(9.4) | 2(11.8) | 9(10.6) | ||||
mucinous | 2(4.2) | 1(1.9) | 2(8.3) | 1(1.3) | 0(0.0) | 3(5.7) | 0(0.0) | 3(3.6) | ||||
Stage | 0.83 | 0.95 | 0.03 | 0.37 | ||||||||
II | 4(8.5) | 5(9.1) | 2(8.3) | 7(9.0) | 2(4.1) | 7(13.2) | 0(0.0) | 9(10.6) | ||||
III | 35(74.5) | 43(78.2) | 18(75.0) | 60(76.9) | 43(87.8) | 35(66.0) | 14(82.4) | 64(75.3) | ||||
IV | 8(17.0) | 7(12.7) | 4(16.7) | 11(14.1) | 4(8.1) | 11(20.8) | 3(17.6) | 12(14.1) | ||||
IV | 8(17.0) | 7(12.7) | 4(16.7) | 11(14.1) | 4(8.1) | 11(20.8) | 3(17.6) | 12(14.1) | ||||
Recurrence | 0.52 | 0.24 | 0.10 | 0.64 | ||||||||
≤ 6M | 10(21.3) | 10(18.2) | 6(25.0) | 14(17.9) | 12(24.5) | 8(15.1) | 3(17.6) | 17(20.0) | ||||
>6M | 23(48.9) | 33(60.0) | 15(62.5) | 41(52.6) | 29(59.2) | 27(50.9) | 11(64.8) | 45(52.9) | ||||
- | 14(29.8) | 12(21.8) | 3(12.5) | 23(29.5) | 8(16.3) | 18(34.0) | 3(17.6) | 23(27.1) | ||||
5-year survival | 0.84 | 0.15 | 0.16 | 0.27 | ||||||||
alive | 17(36.2) | 22(40.0) | 6(25.0) | 33(42.3) | 15(30.6) | 24(45.3) | 4(23.6) | 35(41.2) | ||||
dead | 30(73.8) | 33(60.0) | 18(75.0) | 45(57.7) | 34(69.4) | 39(54.7) | 13(76.4) | 50(58.8) |