Table 1.

Nanoliposome formulations

Formulation	Lipids	Molar ratio
Cationic	DOTAP:PEG2000-DSPE:DOPE	4.75:0.5:4.75
Ghost	DSPC:DOPE:PEG2000-DSPE	5.66:2.87:1.47
Ceramide	DSPC:DOPE:PEG2000-DSPE:PEG750-C8CER:C6CER	3.75:1.75:0.75:0.75:3
Ceramide + PDMP	DSPC:DOPE:PEG2000-DSPE:PEG750-C8CER:C6CER:PDMP	3.75:1.75:0.75:0.75:1.5: 1.5
Basic	DSPC:DOPC:DOPE:PS:SM:CH	0.8:0.8:1:0.4:1: 4
BasicCer	DSPC:DOPC:DOPE:PS:SM:CH:C8CER	0.8:0.8:1:0.4:1:4:1
BasicGluCer	DSPC:DOPC:DOPE:PS:SM:CH:GLUCER	0.8:0.8:1:0.4:1:4:1
BasicCerGluCer	DSPC:DOPC:DOPE:PS:SM:CH:C8CER:GLUCER	0.8:0.8:1:0.4:1:4:1:1

Liposome formulations were prepared from specific lipids, at particular molar ratios, prior to nano-sizing. 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE), 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(methoxy[polyethylene glycol]-2000) (PEG2000-DSPE), 1,2-dioctanoyl-sn-glycero-3-phospho-L-serine (PS), 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP), C6-ceramide (C6CER), C8-ceramide (C8CER), C8-ceramide-1-succinyl[methoxy(polyethylene glycol)-750] (PEG750-C8CER), C8-glucosylceramide (GLUCER), C18-sphingomyelin (SM), cholesterol (CH), and D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP).